Scaling profitably on TikTok requires more than broad targeting, and mastering TikTok audience segmentation strategy for media buyers separates campaigns that hemorrhage budget from those that generate consistent incremental revenue. Most arbitrage operators cast nets that are either too wide—burning money on uninterested users—or too narrow—limiting volume and economies of scale. This resource deconstructs the segmentation methodology into actionable steps: behavioral clustering, lookalike expansion, and seasonal cohort analysis that adapt to TikTok's rapid trends. The guide reveals how to leverage saved audiences, custom audiences, and algorithmic expansion features in tandem to build repeatable scaling templates. Media buyers managing multiple verticals will find the segment documentation and testing protocols especially valuable for building institutional knowledge across accounts.